Colorectal cancer typically starts as polyps in the colon or rectum, according to the American Cancer Society. While many polyps are harmless, some can become cancerous over time.

Once common in older adults, colorectal cancer is now increasingly affecting younger people, prompting changes in screening guidelines.

In 2023, about 153,020 Americans were diagnosed, and over 52,000 died from the disease, making it the second leading cause of cancer-related deaths in the U.S.

Experts believe lifestyle changes since the mid-20th century may be contributing to early-onset cases. One silent risk factor is non-alcoholic fatty liver disease (NAFLD), which often shows no symptoms but is linked to conditions like diabetes and kidney disease.

A South Korean study found that people under 50 with NAFLD are 24% more likely to develop colon cancer. Researchers suggest inflammation from NAFLD may affect the colon and stress the need for earlier screenings and preventive strategies in at-risk populations.